United Kingdom Revised the Cosmetic Products (Restriction of Chemical Substances) Regulations 2023

Chemical Name/INN

Name of Common Ingredients Glossory

CAS number

EC number

Product type, Body parts

Maximum concentration in ready for use preparation

Other

Methyl-N-methylanthranilate

85-91-6

201-642-6

(a) Leave-on products

(b) Rinse-off products

0.1%

0.2%

For leave on products only: Not to be used in sunscreen products and products marketed for exposure to natural or artificial UV light.

For leave-on and rinse-off products: Do not use with nitrosating agents; Maximum nitrosamine content: 50μg/kg; Keep in nitrite-free containers.”

Chemical Name/INN

Name of Common Ingredients Glossary

CAS number

EC number

Product type, Body parts

Maximum concentration in ready-for-use preparation

Other

1,1’-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]-methanone

Bis-(Diethylaminohydroxybenzoyl Benzoyl) Piperazine

919803-06-8

485-100-6

10%

In case of combined use of Bis-(Diethylaminohydroxybenzoyl Benzoyl) Piperazine and Bis-(Diethylaminohydroxybenzoyl Benzoyl) Piperazine (nano), the sum shall not exceed 10%.

1,1’-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]-methanone

Bis-(Diethylaminohydroxybenzoyl Benzoyl) Piperazine (nano)

919803-06-8

485-100-6

10%

Only nanomaterials having the following characteristics are allowed:

- Purity ≥ 97%,

- Median particle size D50 (50% of the number below this diameter): ≥ 50nm of number size distribution.

Not to be used in applications that may lead to exposure of the end user’s lungs by inhalation.

In case of combined use of Bis-(Diethylaminohydroxybenzoyl Benzoyl) Piperazine and Bis-(Diethylaminohydroxybenzoyl Benzoyl) Piperazine (nano), the sum shall not exceed 10%. ”